Wed, 01.09.2021
10:30 AM – 12:30 PM CEST
Room: The ESOC Corner
Chairs: Joanna Wardlaw (United Kingdom) Geert Jan Biessels (Netherlands)

Introduction by the Convenors – LIVE
Prof. Joanna Wardlaw (United Kingdom) & Prof. Geert Jan Biessels (Netherlands)

TRANEXAMIC ACID FOR ACUTE INTRACEREBRAL HEMORRHAGE GROWTH BASED ON IMAGING ASSESSMENT (TRAIGE) – PRE-RECORDED – Dr. Jingyi Liu (China)

1 min break for the convenor to introduce the next presentation

FINAL STUDY REPORT OF ANDEXANET ALFA FOR BLEEDING WITH FACTOR XA INHIBITORS – PRE-RECORDED – Assoc. Prof. Truman John Milling (USA)

1 min break for the convenor to introduce the next presentation

DECOMPRESSIVE NEUROSURGERY FOR PATIENTS WITH SEVERE CEREBRAL VENOUS THROMBOSIS. FINAL RESULTS OF THE DECOMPRESS2 STUDY – PRE-RECORDED
Prof. Sanjith Aaron (India) – 1 min break for the convenor to introduce the next presentation

MULTICENTRE RANDOMISED TRIAL OF ACUTE STROKE TREATMENT IN THE AMBULANCE WITH A NITROGLYCERIN PATCH (MR ASAP) – PRE-RECORDED – Ms. Simone M. Uniken Venema (Netherlands)

1 min break for the convenor to introduce the next presentation

FLYING INTERVENTION TEAM – ASSOCIATION BETWEEN A NOVEL SYSTEM OF CARE FUNCTIONAL OUTCOME OF STROKE PATIENTS IN REMOTE AREAS – LIVE – Dr. Gordian Hubert (Germany)

1 min break for the convenor to introduce the next presentation

MR CLEAN MED – MULTICENTER RANDOMISED CLINICAL TRIAL OF ENDOVASCULAR TREATMENT FOR ACUTE ISCHEMIC STROKE. THE EFFECT OF PERIPROCEDURAL MEDICATION: ACETYLSALICYLIC ACID, UNFRACTIONATED HEPARIN, BOTH OR NEITHER. – PRE-RECORDED – Mr. Wouter Van Der Steen (Netherlands)

1 min break for the convenor to introduce the next presentation

SOLITAIRE™ WITH THE INTENTION FOR THROMBECTOMY PLUS INTRAVENOUS T-PA VERSUS DIRECT SOLITAIRE™ STENT-RETRIEVER THROMBECTOMY IN ACUTE ANTERIOR CIRCULATION STROKE (SWIFT DIRECT): PLACEHOLDER ABSTRACT – LIVE – Prof. Urs Fischer (Switzerland) and Prof. Jan Gralla (Switzerland)

1 min break for the convenor to introduce the next presentation

DIRECT MECHANICAL THROMBECTOMY VERSUS BRIDGING THERAPY – CUMULATIVE STUDY-LEVEL META-ANALYSIS OF THE DIRECT-MT, MR CLEAN-NOIV, DEVT, SKIP AND SWIFT-DIRECT RANDOMIZED CONTROLLED TRIALS – LIVE – Prof. Urs Fischer (Switzerland)

1 min break for the convenor to introduce the next presentation

RESEARCH PRIORITIES IN PREVENTION, DIAGNOSIS, PRE-HOSPITAL AND HOSPITAL CARE FROM A UK JAMES LIND ALLIANCE STROKE PRIORITY SETTING PARTNERSHIP – PRE-RECORDED – Dr. Richard Edward Francis (United Kingdom)

Live Q&A Discussion (25 mins) – All participants to be shown on the screen.

Thu, 02.09.2021
10:30 AM – 12:30 PM CEST
Room: ESOC TV
Convenors: Martin Dichgans (Germany), Else Charlotte Sandset (Norway) and Bart van der Worp (Netherlands)

Introduction by the Convenors – LIVE
Prof. Martin Dichgans (Germany) and Prof. Bart van der Worp (Netherlands)

Announcing the ESO Presidential Awards – Show all 4 award winners on the screen to thank for the awards – LIVE
Dr. Else Charlotte Sandset, (Norway)

ESO Presidential Award:
2021 Awardee
Prof. Michael Brainin (Austria)

2020 Awardee
Prof. Bo Norrving (Sweden)

ESO Scientific Excellence Award:
2021 Awardee
Prof. Georgios Tsivgoulis (Greece)

2020 Awardee
Prof. Urs Fischer (Switzerland)

One of the convenors to introduce the 1st presentation

WHOLE EXOME SEQUENCING REVEALS A ROLE OF THE HTRA1 PROTEASE AND ITS SUBSTRATE EGFL8 IN BRAIN WHITE MATTER HYPERINTENSITIES – PRE-RECORDED – Dr. Rainer Malik (Germany)

Up to 1 min break for the convenor to introduce the next presentation

THE RELATIONSHIP BETWEEN INTRACRANIAL ANEURYSMS GENETIC RISK AND ANEURYSM LOCATION, MULTIPLICITY, AND AGE AT RUPTURE – PRE-RECORDED – Mr. Mark Bakker (Netherlands)

Up to 1 min break for the convenor to introduce the next presentation

RISK OF RUPTURE OF AN INTRACRANIAL ANEURYSM WITH GROWTH DETECTED DURING FOLLOW-UP: A MULTICENTRE COHORT STUDY – PRE-RECORDED – Dr. Laura Tessa Van Der Kamp (Netherlands)

Up to 1 min break for the convenor to introduce the next presentation

MULTITRAIT ANALYSIS EXPANDS GENETIC RISK FACTORS IN CARDIOEMBOLIC STROKE – PRE-RECORDED – Ms. Jara Cárcel-Márquez (Spain)

Up to 1 min break for the convenor to introduce the next presentation

BENEFITS AND RISKS OF STATIN THERAPY IN THE SECONDARY PREVENTION OF PATIENTS WITH ISCHEMIC STROKE AND CEREBRAL MICROBLEEDS – INDIVIDUAL-PATIENT DATA ANALYSIS OF PROSPECTIVE COHORT STUDIES – PRE-RECORDED – Dr. Luis Prats-Sánchez (Spain)

Up to 1 min break for the convenor to introduce the next presentation

PREDICTORS FOR COGNITIVE DECLINE AND DEMENTIA IN PEOPLE WITH PRIOR STROKE/TRANSIENT ISCHEMIC ATTACK – PRE-RECORDED – Ms. Jessia Gong (Australia)

Up to 1 min break for the convenor to introduce the next presentation

ASSOCIATION BETWEEN ORAL ANTICOAGULANTS AND THE RISK OF DEMENTIA IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION – PRE-RECORDED
Mr. Alvi Anan Rahman (Canada) – Up to 1 min break for the convenor to introduce the next presentation

CEREBRAL VENOUS THROMBOSIS AFTER VACCINATION AGAINST COVID-19 IN THE UK: A MULTICENTRE COHORT STUDY – PRE-RECORDED – Dr. Richard. J. Perry (United Kingdom)

Live Q&A Discussion (25 mins) – All participants to be shown on the screen.

Fri, 03.09.2021
04:15 PM – 06:30 PM CEST
Room: The ESOC Corner
Chairs: Peter Kelly (Ireland) and Mira Katan (Switzerland)

Introduction by the Convenors – LIVE
Dr. Mira Katan (Switzerland) and Prof. Peter Kelly (Ireland)

APACHE-AF: APIXABAN VERSUS ANTICOAGULATION AFTER ANTICOGULATION-ASSOCIATED INTRACEREBRAL HAEMORRHAGE IN PATIENTS WITH ATRIAL FIBRILLATION: A RANDOMISED, OPEN-LABEL, PHASE 2 TRIAL. – PRE-RECORDED – Dr. Floris Schreuder (Netherlands)

Up to 1 min break for the convenor to introduce the 1st presentation

EFFECTS OF LONG-TERM ORAL ANTICOAGULATION FOR ATRIAL FIBRILLATION AFTER SPONTANEOUS INTRACRANIAL HAEMORRHAGE: THE START OR STOP ANTICOAGULANTS RANDOMISED TRIAL (SOSTART) – PRE-RECORDED – Prof. Rustam Al-Shahi Salman, (UK)

Up to 1 min break for the convenor to introduce the next presentation

SHORT-TERM SYSTOLIC BP VARIABILITY AND FUNCTIONAL OUTCOME AFTER ACUTE ICH: ANALYSES OF POOLED INDIVIDUAL PARTICIPANT DATA – PRE-RECORDED – Dr. Tom Moullaali (UK)

Up to 1 min break for the convenor to introduce the next presentation

EFFECTS OF ANTIPLATELET THERAPY AFTER STROKE DUE TO INTRACEREBRAL HAEMORRHAGE: EXTENDED FOLLOW-UP OF THE RESTART OR STOP ANTITHROMBOTICS RANDOMISED TRIAL (RESTART) – PRE-RECORDED – Prof. Rustam Al-Shahi Salman, (UK)

Up to 1 min break for the convenor to introduce the next presentation

WHEN TO INITIATE DUAL ANTIPLATELET THERAPY USING CILOSTAZOL FOR SECONDARY PREVENTION IN HIGH-RISK ISCHEMIC STROKE: CSPS.COM – PRE-RECORDED – Dr. Kazunori Toyoda, (Japan)

Up to 1 min break for the convenor to introduce the next presentation

ISCHEMIC BENEFIT AND HEMORRHAGE RISK OF TICAGRELOR-ASPIRIN VS. ASPIRIN IN PATIENTS WITH ACUTE ISCHEMIC STROKE OR TIA – PRE-RECORDED  – Dr. S. Claiborne Johnston (USA)

Up to 1 min break for the convenor to introduce the next presentation

NEUROREGENERATION ENHANCED BY TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) IN STROKE (NETS) – PRE-RECORDED – Prof. Christian Gerloff (Germany)

Up to 1 min break for the convenor to introduce the next presentation

TIMING OF ORAL ANTICOAGULANT THERAPY IN ACUTE ISCHEMIC STROKE WITH ATRIAL FIBRILLATION: A REGISTRY-BASED RANDOMISED CONTROLLED STUDY – LIVE – Prof. Jonas Oldgren (Sweden) and Assoc. Prof. Signild Åsberg (Sweden)

Live Q&A Discussion (25 mins) – All participants to be shown live on the screen.

ESO Angels Awards – video

Announcing of Young Investigator Awards & Rapid Oral Communication Prizes – LIVE – 1-2 slides with the pictures of the award winners – Martin Dichgans & Bart van der Worp

Closing Ceremony (10-15 mins):
• Closing words from Prof. Joanna Wardlaw including Outlook to 2022 – LIVE
• ESOC 2022 – video (1.5 minutes)
• Welcome words to ESOC 2022 from Prof. Norbert Nighoghossian including 4 ppt slides – LIVE – (approx. 2-3 minutes)
• Final goodbye from Prof. Wardlaw – LIVE

Date: Wed, 01.09.2021
Session Time: 08:30 AM – 10:00 AM CEST
Room: Hall A

Session Description: Focused workshop directed to young investigators. The main aim is to support young stroke researchers in promoting their research projects under construction to the wider stroke community and to have their proposed study design reviewed in an open forum and by an expert mentor in the field.
Chairs: Diana Aguiar de Sousa (Portugal) Nicolas Martinez-Majander (Finland)

Introduction by the Convenors – Live
Diana Aguiar De Sousa; Nicolas Martinez-Majander, (Portugal, Finland)

Getting Your First Grant – Pitfalls and Challenges – Live
Marcel Arnold, (Switzerland)

Up to 1 min break for the convenor to introduce the next presentation

Saying “Yes” or Saying “No” – When and How? – Pre-recorded
Valeria Caso, (Italy)

Up to 1 min break for the convenor to introduce the next presentation
DATA-DRIVEN MACHINE LEARNING ANALYSIS TO DEVELOP OUTCOME PREDICTION TOOLS IN PATIENTS UNDERGOING THROMBECTOMY FOR POSTERIOR CIRCULATION ACUTE ISCHEMIC STROKE: RATIONALE AND STUDY-DESIGN – Pre-recorded
Alexander Salerno; (Switzerland)

Up to 1 min break for the convenor to introduce the next presentation

ASSESSING COVERT BRAIN INFARCTION IN PATIENTS WITH ACUTE INTRACEREBRAL HEMORRHAGE: AN EVACUATE IMAGING SUB-STUDY – Pre-recorded
Vignar Yogendrakumar; (Australia)

Up to 1 min break for the convenor to introduce the next presentation

PILOT-STUDY FOR SLEEP APNEA SYNDROME TREATMENT IN ACUTE CEREBRAL INFARCTION: THE PISTACIO TRIAL – Pre-recorded
Ines Pecot; (France)

Up to 1 min break for the convenor to introduce the next presentation

EXPLORING MARKERS OF STROKE CARE AND STROKE ASSOCIATED PNEUMONIA IN STROKE UNITS ACROSS ENGLAND AND WALES – Pre-recorded
Marco Antonio Lobo Chaves; (United Kingdom)
Up to 1 min break for the convenor to introduce the next part of the session

General Advice from the Assigned Mentor – Live
Marcel Arnold, (Switzerland)

General Advice from the Assigned Mentor – Live
Valeria Caso, (Italy)

Live Q&A Discussion (10 mins) – All participants will be shown live on the screen.

Wed, 01.09.2021
03:15 PM – 04:45 PM CEST
Room: Hall A

Session Description: This will be a highly practical session on publishing in stroke journals. The first two talks will cover guidance for the delegate on how to increase their chances of success by optimal preparation of a paper before submission, and to explain how the journal processes work and what can be done to increase the chance of acceptance. This will be followed by a session on how to review a paper, including opportunities available for reviewer training, such as the early career support provided by Stroke journal. It will finish with a talk on the many changes and challenges that are occurring in publishing, and a gaze into the future as to what the format of publishing will look like in 10 years time.
Convenors: David Z. Wang (USA) and Karin J. Klijn (Netherlands)

Welcome by the convenors – LIVE
David Z. Wang; Karin Klijn, (USA, Netherlands)

How to Prepare a Paper for Submission? – Pre-recorded
Bo Norrving, (Sweden)

What Happens After Submission? – Pre-recorded
Hugh Markus, (UK)

How to Review a Paper? – Pre-recorded
Ralph Sacco, (USA)

The Future of Publishing – Pre-recorded
Helen Frankish, (UK)

Live Q&A Discussion with all speakers – ~28 mins

Up to 1 minute break between the pre-recorded talks for the convenors to introduce the next presentation.

Date: Thu, 02.09.2021
Session Time: 03:45 PM – 05:15 PM CEST
Room: Hall A
Session Description: This session aims to discuss and debate current topics of importance to stroke in a lively and stimulating forum.
Convenors: Dr. Tiina Sairanen (Finland) and Prof. Malcolm Macleod (UK)

FORMAT:
Your session will be in a TV studio format. This means that the presentations will be pre-recorded and streamed during the scheduled session slot (2nd September @15:45 – 17:15 CEST).
1. The session will start with live welcome by the convenors. They will need to present the first debate question ‘The computer says ’’No’’. This house believes that all hospitals should use automated software on all patients with suspected stroke in order to guide treatment.’ and encourage the audience to vote YES or NO via a Slido link which will be posted in the chat field for attendees to see.
2. After that the first two speakers will present their talks – George Harston (FOR) and David Liebeskind (AGAINST).
3. The session will continue with Live Q&A, moderated by the convenors. They should prepare own questions which to trigger a debate, but also select a few questions from the posted ones in the chat field. Attendees will be able to upvote questions they want to see answered. Convenors will have access to the chat field and be able to monitor the received questions while the pre-recorded presentations are streamed on the screen.
4. At the end of the 1st round, the convenors will introduce revoting of the same question. This is to estimate how the audience’s opinion has changed after the two talks and the discussion.
5. The same process will repeat for the other debate question.

Welcome by the convenors – LIVE
Dr. Tiina Sairanen (Finland) and Prof. Malcolm Macleod (UK)
First voting question to be presented – ‘The computer says ’’No’’. This house believes that all hospitals should use automated software on all patients with suspected stroke in order to guide treatment.’
A few seconds for the audience to vote with YES or NO and to show the results on the screen.
Convenors to present the first talk and encourage the audience to submit questions via the chat feature for the Live Q&A which will take place after the 2 talks.

FOR: ‘The computer says ’’No’’. This house believes that all hospitals should use automated software on all patients with suspected stroke in order to guide treatment.’ – Pre-recorded
George Harston, (United Kingdom)

Up to 1 minute break for the convenor to introduce the second speaker

AGAINST: ‘The computer says ’’No’’. This house believes that all hospitals should use automated software on all patients with suspected stroke in order to guide treatment.’ – Live
David Liebeskind (USA)

Audience Q&A (15 mins)

Revote the same question and show the results on the screen 

~THE NEXT DEBATE SHOULD START AT 16:30 CEST ~

Convenors to present the 2nd debate – Live
Second voting question to be presented – ‘Doctor, I have white spots in my brain – what should I do?’ ‘This house believes that all patients with white matter lesions of presumed vascular origin should receive antihypertensive treatment.’
A few seconds for the audience to vote with YES or NO and to show the results on the screen.
Convenors to present the first talk and encourage the audience to submit questions for the Live Q&A which will take place after the 2 talks.

Up to 1 minute break for the convenor to introduce the next debate question and the first speaker

FOR: ‘Doctor, I have white spots in my brain – what should I do?’ ‘This house believes that all patients with white matter lesions of presumed vascular origin should receive antihypertensive treatment.’ – Pre-recorded
Christopher Chen, (Singapore)

Up to 1 minute break for the convenor to introduce the second speaker

‘This house believes that all patients with white matter lesions of presumed vascular origin should receive antihypertensive treatment.’ – Pre-recorded
Alastair Webb, (United Kingdom)

Audience Q&A (15 mins)

Revote the 2nd question and show the results on the screen

Conclusion by the convenors – Live

Fri, 03.09.2021
08:30 AM – 10:00 AM CEST
Room: Hall A
Convenors: Prof. Simona Sacco (Italy) and Prof. Guillaume Turc (France)

Introduction by the Convenors – Live
Prof. Simona Sacco (Italy) and Prof. Guillaume Turc (France)

ESO Guideline on Dissections – Pre-recorded
Prof. Stéphanie Debette (France)

ESO and EAN Joint Guideline Post Stroke Cognitive Impairment – Pre-recorded
Dr. Terence J. Quinn (United Kingdom)

ESO and ESSD Guideline for the Diagnosis and Treatment of Post-Stroke Dysphagia – Pre-recorded
Prof. Rainer Dziewas (Germany)

Live Q&A Discussion (25 mins) – All participants to be shown live on the screen.